Planas A, Clarà A, Marrugat J, Pou JM, Gasol A, de Moner A, Contreras C, Vidal-Barraquer F,

Age at onset of smoking is an independent risk factor in peripheral artery disease development.

J. Vasc. Surg. 2002 Mar; 35 (3): 506-9, PMID: 11877699

The potential effects of age at onset of smoking on cardiovascular diseases have been studied little, in contrast to the well-established evidence supporting a causal role of cigarette smoking in these diseases. We sought to analyze the relationship between age at smoking onset and development of symptomatic peripheral arterial occlusive disease (PAOD).

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